Delirium due to sepsis-associated encephalopathy mimicking alcohol withdrawal delirium

Sepsis-associated encephalopathy: not just delirium

Sepsis is a major cause of mortality and morbidity in intensive care units. Organ dysfunction is triggered by inflammatory insults and tissue hypoperfusion. The brain plays a pivotal role in sepsis, acting as both a mediator of the immune response and a target for the pathologic process. The measurement of brain dysfunction is difficult because there are no specific biomarkers of neuronal injur...

Acute Alcohol Withdrawal and Delirium Tremens

Acute Alcohol Withdrawal and Delirium Tremens

Acute Alcohol Withdrawal and Delirium Tremens

Pellagrous encephalopathy presenting as alcohol withdrawal delirium: A case series and literature review

BACKGROUND Alcohol withdrawal delirium (AWD) is associated with significant morbidity and mortality. Pellagra (niacin deficiency) can be a cause of delirium during alcohol withdrawal that may often be overlooked. OBJECTIVES We present a three-patient case series of pellagrous encephalopathy (delirium due to pellagra) presenting as AWD. METHODS We provide a brief review of pellagra's history...